Stomach physiology

1.Vagus nerve→ M3 receptor→ Gq→ IP3/Ca→ H-K pump

2.G cells→ gastrin→ CCKb receptor→ Gq→ IP3/Ca→ H-K pump

3.G cells→ gastrin→ ECL cell→ Histamine→ H2 receptor→ Gs→ cAMP→ H-K pump

4.PGE→ Gi→ inhibit cAMP→ H-K pump

*Somatostatin– Inhibit ECL cells(secretes histamine), G cells

*Chief cell→ Pepsinogen I and II

*Parietal cell→ HCL, intrinsic factor

*Mucosal cell→ Mucus, pepsinogen II, bicarbonate

*D cell→ Somatostatin

Published by Steve Johnson

I am a doctor who like to organise knowledges and share ideas with others. As a doctor, a lot of knowledges influx everyday and need some patient to organise and absorb. Here was my notes to share with you and hope to save your time to know it.

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