Definition- Male<13, Female<12

Reticulocyte production index= (Ret.count) x (Hct/45) x (1/maturation correction), <2% indicate bone marrow problem

MCV= (Hct x 10)/RBC count


1.WBC/PLT decreased→ infection, drug, renal disease, splenomegaly, leukemia, aplastic anemia

2.WBC/PLT normal→ infection, drug, renal disease, Diamond-Blackfan anemia, hypoplastic anemia

1.Microcytic(MCV<80) IDA,thalassemia, chronic inflammation, sideroblastic, lead intoxication, copper/zinc deficiency

2.Normocytic(MCV 80~100)- bone marrow suppression, CRF, hypopituitarism, hypothyroidism, acute blood loss, chronic inflammation, IDA(early), pure red cell aplasia

3.Macrocytic(MCV>100)- ethanol, AML, reticulocytosis, MDS, liver disease, hypothyroidism, AZT, Lesch-Nyhan syndrome

Published by Steve Johnson

I am a doctor who like to organise knowledges and share ideas with others. As a doctor, a lot of knowledges influx everyday and need some patient to organise and absorb. Here was my notes to share with you and hope to save your time to know it.

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