Aplastic anemia

前言3 peaks→ 2~5y/o, 20~25y/o, 55~60y/o

Etiology- Fanconi anemia(咖啡牛奶, 性腺功能低下, 小頭症), Dyskeratosis congenita(neutropenia, nail dystrophy, leukoplakia, pigmented skin), Shwachman-Diamond(neutropenia, pancreatic exocrine dysfunction, short stature), chemotherapy, parvovirus B19, HIV, EBV, SLE, gold, NSAID, 抗癲癇, sulfonamide, benzene, pregnancy, thymoma, PNH

Diagnosis

1.取2- ANC<500, Ret<1%, PLT<20000

2.取1- Bone marrow cellularity< 25%, Bone marrow cellularity< 50% with <30% hematopoietic 

Treatment

1.嚴重- Bone marrow transplant(<40 y/o) or ATG + cyclosporin + steroid

2.中, 輕微- Steroid

3.支持療法- 輸血

Published by Steve Johnson

I am a doctor who like to organise knowledges and share ideas with others. As a doctor, a lot of knowledges influx everyday and need some patient to organise and absorb. Here was my notes to share with you and hope to save your time to know it.

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