Thrombocytosis and thrombocytopenia

Thrombocytosis Etiology- GI bleeding, IDA, JAK2 先測試JAK2, MPL, CALR, 不是gene問題後→ Hydroxyurea, aspirin Thrombocytopenia Etiology 1.Splenomegaly→ Normal BM(liver cirrhosis), abnormal BM(Leukemia, lymphoma) 2.Normal spleen→ Normal BM(ITP, TTP, DIC, HIT, APS, HUS, pregnancy, Kasabach-Merritt syndrome, HIV, malignancy, trisomy 13,18, methylmalonic acidemia, Bernard-Soulier, WAS, burns, hypothermia), abnormal BM(aplastic anemia, PNH)